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Safety endpoints included the number of treatment-emergent adverse events and serious adverse events, assessed between baseline and week 111

Patients treated with GLP-1 RAs had a lower risk of serious renal events than those treated with dipeptidyl peptidase 4 inhibitors (HR 0.76, 95% CI 0.680.85) [57]

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in its active form (thiamine diphosphate), it is an essential cofactor for enzymes in glucose and amino acid catabolism, helping convert nutrients into ATP and supporting normal neuronal function

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