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Peptide therapy for weight loss involves using specific peptidesshort chains of amino acids, aka the building blocks of proteinto help regulate hormones, control appetite, and influence fat metabolism

Its physiological actions include stimulating glucose-dependent insulin secretion from pancreatic beta cells, suppressing glucagon release, slowing gastric emptying, and promoting satiety through central nervous system pathways

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While the half-dozen men who spoke to me for this story largely said they had good experiences with compounded weight-loss drugs, doctors are concerned about the widespread use of compounded medications