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The 5-day half-life applies regardless of weight

It is important to remember that whether you use a pen or a vial, the active ingredient remains the same

Sitagliptin in Combination with Metformin Immediate-Release and Insulin In a 24-week placebo-controlled study of sitagliptin 100 mg as add-on therapy in patients with type 2 diabetes inadequately controlled on metformin immediate-release and insulin (sitagliptin, N=229

On convenience , oral wins decisively

Most gastrointestinal side effects are dose-dependent and tend to be most pronounced during the initial weeks of treatment or following dose escalation

These include anyone with a history of alcohol use disorder (alcohol withdrawal or dependence increases risk during medication use), patients taking concurrent diabetes medications that lower blood sugar, and those with liver disease or reduced liver function