Mechanistically, autoantibodies and interferon- present in the serum induce neutrophil ferroptosis through enhanced binding of the transcriptional repressor CREM to the glutathione peroxidase 4 ( Gpx4 , the key ferroptosis regulator) promoter, which leads to suppressed expression of Gpx4 and subsequent elevation of lipid-reactive oxygen species
Leaky gut or increased intestinal permeability (its proper name) is one of those areas where the science is well ahead of mainstream awareness
Increased pigmentation of freckles or moles has been reported
Semaglutide sold under brand names like Ozempic and Wegovy reduces appetite and lowers the desire for energy-dense, salty, and spicy foods, the researchers said
Conversely, when switching to semaglutide from shorter-acting agents, the gradual onset of full therapeutic effect (4 to 5 weeks to steady state) must be considered
KATHERINE ARMOUR: It's concerning because so many, particularly young people, of course, do use social media as a common way to research their topics of interest
