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Even without genetic variations, constant stress, like from toxins or environmental causes, also affects the activity of genes and, therefore, the enzymes

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Patients and/or caregivers should discard any unused portion Patients and/or caregivers should store DUPIXENT by refrigerating at 36 F to 46 F (2 C to 8 C) in the original carton to protect from light If necessary, DUPIXENT may be kept at room temperature up to 77 F (25 C) for a maximum of 14 days

Am J Clin Nutr 2005, 82: 553-558

I use one of the test strips every month to monitor my water softeners performance to help protect my appliances