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In: Pantopoulos K, Schipper HM, editors

The extra weight leads to an increase in the NNMT enzyme, leading to slower fat metabolism, leading to excess weight gain

Klobuar S, Kenel Jovanovi G, Kryczyk-Kozio J, Cigrovski Berkovi M, Vuak Lonar J, Mori N et al (2024) Association of Dietary Inflammatory Index and Thyroid Function in Patients with Hashimotos Thyroiditis: An Observational Cross-Sectional Multicenter Study

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However, the "top-down" approach only works if you use a high-bioavailability format

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