61 In addition, Exendin-4 quickly enters the brain and brain microvascular endothelial cells via active ligands that bind to and activate GLP-1 receptors
Originally, GLP-1 likely evolved to control metabolism or processes linked to feeding status, says Karolina Skibicka PhD, professor of nutritional neuroscience at the Hotchkiss Brain Institute, University of Calgary
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Evidence that the major degradation product of glucose-dependent insulinotropic polypeptide, GIP(3-42), is a GIP receptor antagonist in vivo