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The total for the 12 weeks was $717

Methodology A literature review of PubMed and Google Scholar was performed to obtain available evidence on the efficacy and safety of oral semaglutide and its recommendations

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In ATTAIN-1, the 17.2mg dose produced 11.1% weight loss over 72 weeks (non-diabetic participants) vs SURMOUNT-1's 20.9% for Zepbound 15mg

Many patients report experiencing cravings they hadn't felt in months, alongside a restoration of the appetite that initially drove weight gain

Medication Mechanism of Action Average Weight Loss Retatrutide Triple agonist (GLP-1, GIP, Glucagon) Up to 24% average weight loss over 48 weeks Semaglutide GLP-1 receptor agonist Up to 17% over 68 weeks Tirzepatide Dual agonist (GLP-1, GIP) Up to 25% over 52 weeks Retatrutide is used to help with weight loss