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Conclusion In summary, levocarnitine plays an important role in fatty acid metabolism, acting as a shuttle to transport long-chain fatty acids into mitochondria for breakdown and energy production

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Since protein synthesis and oxygen-dependent protein folding are energy-intensive processes, and hypoxia significantly reduces the level of intracellular ATP, regulating mRNA translation is an important cellular response to hypoxia (71, 72)

TGF- induces GLS1 via the PI3K/mTORC2/PDGFR signaling pathway, promoting fibrotic target expression [100]

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On top, MD snapshots from the respective active sites are shown highlighting R359 and F360