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Many patients are on a combination of an SGLT2 inhibitor with a GLP-1 receptor agonist or tirzepatide (a dual agonist) and have incredible success without adverse reactions, but we are still figuring out the patient characteristics that would put them at higher risk of poor outcomes. Eli J

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As facial fat volume diminishes alongside overall weight reduction, many patients present with new or accelerated concernsmost notably midface volume loss, skin laxity, and deepening wrinkles or foldsdriving increased demand for non-surgical facial rejuvenation and multimodal treatment strategies

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And thats where newer medications are effective, he added.