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Orlistat and cyclosporine should not be simultaneously co-administered Patients should be strongly encouraged to take a multivitamin supplement that contains fat-soluble vitamins to ensure adequate nutrition because Orlistat has been shown to reduce the absorption of some fat-soluble vitamins and beta-carotene Rare cases of severe liver injury with hepatocellular necrosis or acute hepatic failure have been reported, with some of these cases resulting in liver transplant or death Patients may develop increased levels of urinary oxalate following treatment with Orlistat

No statistically significant differences between the formulations were observed, and safety profiles were comparable

DHA diet reduces AD pathology in young APPswe/PS1delta E9 transgenic mice: possible gender effects

doi: 10.1186/s12906-017-2011-x 7 DresslerNChandraAAguirre DavilaLSpineliLMSchippertCvon Versen-HoynckF

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