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The other is the action of the excipients in stimulating enterocytes to take up material from the extra-cellular fluid by a process of vacuolation

Gradient started 90% B, decreased to 65% B at 10 min, further decreased to 20% B at 11.5 min, kept at 20% B until 13 min, returned to 90% B at 14 min and kept at 90% B until 20 min

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Additionally, pramlintide has been approved as adjunct to insulin therapy for treatment of type 1 and type 2 diabetes due to its ability to regulate post-prandial glucose levels, reduce body weight, and HbA1c [34, 37, 42]

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