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In contrast to PDGF-BB, in diabetic wounds, induced by alloxan application, BPC 157 largely promoted mature collagen in granulation tissue (Seveljevic-Jaran et al., 2006) (note, previously, BPC 157 healed alloxan-induced gastric lesions in rats (Petek et al., 1999))

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FDA Regulatory Framework The FDAs position centers on two realities: (1) BPC-157 is not an approved drug, and (2) FDA has raised safety concerns related to compounding it from bulk substance

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Saline adds a different problem: the sodium chloride can interact with some peptide chemistries and provides no bacteriostatic activity

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