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While no specific diet has been shown to be superior in clinical trials among Wegovy users, human clinical evidence indicates that whole-food diets are the most effective for supporting weight loss and overall health

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At the cellular level, coptisine exerts dose-dependent cytotoxicity in HepG2 and 3T3-L1 cells, with IC 50 values of 64.81 g/mL and 56.48 g/mL, respectively, showing cytotoxicity only at relatively high concentrations (Yi et al., 2013)

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doi:10.1056/NEJMoa2032183

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