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At a population level, otherwise healthy individuals going down the path of lifelong dependency on a medication with major side effects is concerning

doi: 10.1016/j.amjmed.2025.01.021 5 NauckMAMeierJJ

GLP-1 medications are a class of medications known as glucagon-like peptide-1 (GLP-1) receptor agonists

The connection between GLP-1 and vision loss extends beyond NAION to include several other eye-related issues: Optic neuropathy : Damage to the optic nerve affecting signal transmission from the eye to the brain Retinal ischemia : Inadequate blood supply to the retina causing tissue damage Diabetic retinopathy exacerbation : Acceleration of existing retinal blood vessel damage in diabetic patients Extensive Research: Indicates that patients using semaglutide-based medications face elevated risks of developing these GLP-1 eye problems

If blood sugar levels are controlled, this decreases the risk of type 2 diabetes

Owing to a 2017 settlement with AbbVie, Amjevita had several months of exclusivity on the US market