More importantly, we focus on the cutting-edge nanotechnology in view of ROS-related PIPN mechanisms and will discuss the rational fabrication of tailor-made nanosystems for efficiently preventing and treating PIPN
This synthetic 11-amino-acid peptide, also known as cibinetide, has completed multiple human clinical trials specifically targeting neuropathy, with results that have attracted FDA Fast Track designation and orphan drug status
Kajimoto Y, Kaneto H (2004) Role of oxidative stress in pancreatic beta-cell dysfunction
Vasodilator action of angiotensin-(17) on isolated rabbit afferent arterioles
Sci China Life Sci 63:14131416 Nieto-Torres JL, Verdi-Bguena C, Jimenez-Guardeo JM, Regla-Nava JA, Castao-Rodriguez C, Fernandez-Delgado R, Torres J, Aguilella VM, Enjuanes L (2015) Severe acute respiratory syndrome coronavirus E protein transports calcium ions and activates the NLRP3 inflammasome
"Glutathione Depletion Accelerates Cigarette Smoke-Induced Inflammation and Airspace Enlargement." Toxicol Sci