GLP-1 helps your body: Increase insulin secretion when glucose is present Improve post meal blood sugar control Slow gastric emptying so you feel fuller longer Signal satiety to the brain GLP-1 receptor agonist medications mimic this hormone
And now the research confirms that this same plate maximizes your bodys natural GLP-1 production
Meanwhile, people with PCOS tend to have elevated levels of testosterone, which can affect the egg follicles in your ovaries, increase insulin resistance, and encourage fat storageall of which can throw off your ovulation
The practical implication is that if you tolerated semaglutide or tirzepatide well, you will likely tolerate retatrutide at equivalent GLP-1 activity levels
Balanced activation can assist in fat burning and reducing liver fat
The glucagon receptor component does introduce metabolic adaptation over time, and varying the stimulus could theoretically disrupt adaptation