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Pineal Extract Research Researchers studied Epithalamin, a peptide-containing preparation isolated from bovine pineal tissue, in ageing and neuroendocrine models

Arthritis & Rheumatology by Joseph F Merola and colleagues evaluated whether combining ixekizumab (IXE), an IL-17 inhibitor, with tirzepatide (TZP), a GLP-1 receptor agonist, could offer enhanced clinical benefits compared to ixekizumab alone in adults with active PsA and excess weight

Purification by reverse-phase chromatography brings the peptide to the 99% release specification, after which lyophilization into 10 mg vials completes the build cycle on Canadian soil

It therefore remains important to distinguish whether their neuroprotective potential arises from direct CNS actions or from peripheral metabolic improvements that indirectly benefit the brain

This distinction matters most for patients who switch between medications or use both in sequence

[DOI] [PMC free article] [PubMed] [Google Scholar] 47.Zelniker TA, Wiviott SD, Raz I, Im K, Goodrich EL, Furtado RHM, et al