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As a result, differences in background glucose-lowering treatments, weight-modifying therapies, and clinical characteristics across trials may have influenced observed weight-loss responses

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The data suggested that release of the cysteine moiety of GSH is critical for the restoration of transcriptional response to cystine starvation, which corroborated the signaling result of p-GCN, p-eIF2 and notably ATF4, which induces the expression of genes containing AARE (Fig

Baxter, Brandon (June 3, 2014)