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7) Liver Dysfunction In a study on over 1,600 adults, high TMAO levels were associated with more severe liver damage and non-alcoholic fatty liver disease [33]

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Our findings of decreased NRF2 levels seem to contradict previous studies suggesting an increased NRF2 response in Down syndrome

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[5] [7] Patients should be aware of symptoms such as right upper abdominal pain, fever, or yellowing of the skin or eyes, which warrant prompt medical assessment