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Duration matters significantly: short-term prednisone courses (1014 days) create minimal metabolic conflict, while chronic use (months or years) substantially undermines semaglutide's effectiveness

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Cellular Defence Helps reduce oxidative damage caused by stress, pollution, or illness

Astrocytes also establish functional, metabolic, and physical contacts with surrounding cells, including neighboring astrocytes, neurons, and endothelial cells of blood vessels

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