Consistent with the in vivo results, HU inhibited BAX by upregulating BCL2 expression levels in HG-treated HRMC cells, thereby attenuating apoptosis
Amino Acids 43 (3), 13311337
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Ferroptosis inhibitors can rescue apoptosis caused by iron overload, whereas apoptosis inhibitors cannot prevent death, and the underlying mechanism may be related to the p53 signaling pathway [186]
Both -3 and -6 PUFA are essential components of phospholipid membranes and precursors of inflammatory mediators with opposing effects: -6 PUFA promote inflammation while -3 PUFA tend to inhibit it
Cancer 116(19):4487-94, 2010