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In the SURMOUNT-1 trial, patients lost an average of 22.5% of body weight over 72 weeks

Lactic Acidosis: Metformin can rarely cause a serious and life-threatening condition called lactic acidosis (too much lactic acid in the blood)

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Mitochondrial Oxidative Capacity AOD-9604 substantially increases whole-body fat oxidation with elevated plasma glycerol levels (an index of lipolysis)

If you encounter nausea and vomiting, eat frequently but in smaller portions