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Increased clearance of IgG in mice that lack beta(2)-microglobulin: possible protective role of FcRn

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A double-blind, placebo-controlled trial on CB4211, which is an analog (synthetic version) of MOTS-c, found the compound to be "safe and well tolerated" under a single and multiple ascending dose protocol in adult humans

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After pushback from the compounding pharmacies, the agency agreed to reevaluate its decision, but in December 2024, it announced it would be sticking with its original call