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Furthermore, GLP-1 RA-related NAEs are likely to occur in the early stages of treatment, mirroring the temporal trajectory of psychiatric 19 , gastrointestinal 36 , and ophthalmic 37 AEs associated with these agents, and emphasizing vigilance during treatment initiation phase

Insulin increases liver GHR expression, making the liver more GH-sensitive, leading to an increase in IGF-1 and a decrease in GH

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Vitamin C is a critical cofactor for collagen synthesis