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The design bet was that balanced glucagon activity, offset by strong GLP-1 and GIP glucose-lowering, could capture those effects without the hyperglycemia

Chromatogram Visuals: A single, sharp peak indicates a clean sample

Heterogeneity among SNPspecific estimates was evaluated using Cochrans Q test and quantified by the I statistic

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Residues of the agonist are indicated by the chain (P) denotation and GLP-1R residues are indicated by the (R) denotation