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A single-chain antibody-CD39 fusion protein targeting activated platelets protects from cardiac ischaemia/reperfusion injury

Ali, a Spanish surgeon, was the first physician to perform itinitially for therapeutic purposes, like retinal detachment and cases of albinism, before moving into cosmetic purposes

We are grateful to the patient with the R152H variant and the patients parent for providing their fibroblasts for this study

However, delivery across the blood-brain barrier remains a major challenge requiring innovative approaches