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Any therapy that sustains high IGF-1 raises a theoretical concern about promoting the growth of existing or nascent tumors

Common MTHFR-only approach An MTHFR variant is identified Methylfolate or folinic acid is recommended Anxiety, insomnia or depression worsens The reaction is labeled detox The actual biochemical pattern remains unidentified More complete functional approach Review the mood, anxiety and behavioral phenotype Assess previous reactions to folate and methyl donors Measure whole blood histamine and SAM/SAH Evaluate homocysteine, copper, zinc and pyrroles Consider inflammation, gut health and toxic burden Select nutrients according to the complete pattern Where Folate Reactions Fit Within the Five Walsh Biotypes The Walsh Approach does not ignore genetics

Worsening macrocytic anemia : B 12 deficiency may also cause a macrocytic (megaloblastic) anemia BUT, in the presence of folate supplementation, this anemia may be masked so that B 12 deficiency may present with exclusively neurologic features

Brigelius-Flohe R, Kipp A

In cases of injury in rats involving the mesenteric vein and pancreaticoduodenal vein, the blood vessel recruitment and angiogenesis induced by BPC-157 potentially contributed to reducing ischemia and mucosal injury in the abdominal organs

Possible BPC-157 risks including tumors Taking these peptides will pose risks