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OARSI pathological scoring confirmed higher scores in the OA group compared to the sham group, whereas metformin treatment resulted in a numerically lower OARSI score than that of the OA group, although the difference was not statistically significant (Fig

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doi: 10.1186/s40104-021-00545-7 362 HuangJChenBLiHZengQHWangJJLiuHet al

To date, the only human trial involving ipamorelin was just 7 days long [5], which is clearly insufficient to draw any conclusions about this peptide's long-term side effects

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Its weight loss properties stem from its ability to decrease appetite and slow gastric emptying, which can help individuals feel fuller for longer, thereby reducing caloric intake