You should contact your GP if: Your B12 level is significantly elevated (markedly above your local laboratory's reference range) without obvious explanation such as supplementation You have persistent elevation on repeat testing You experience unexplained symptoms such as unintentional weight loss, persistent fatigue, night sweats, fever, or abdominal discomfort You notice unusual bruising, bleeding, or enlarged lymph nodes You have jaundice (yellowing of skin or eyes) or other signs of liver disease You have a history of liver disease, kidney disease, or blood disorders Immediate medical attention (contact NHS 111 or attend A&E) is warranted if you experience severe symptoms such as significant bleeding, severe abdominal pain, confusion, or signs of acute illness, though these would rarely be directly related to elevated B12 itself

Heres a quick summary on GLP-1s and various eye conditions, and what experts have to say about them: NAION NAION causes sudden blindness in one eye, usually after waking, that is caused by a lack of blood flow to the optic nerve
[DOI] [PubMed] [Google Scholar] 38.Alberghina M, Lupo G, La Spina G, et al
Samples were subsequently analyzed for Glucose-6-phosphate and Fructose-6-phosphate levels following the manufacturers instructions respectively from MAK014 and MAK020 Assay Kits (Sigma)
There is currently limited clinical research on combining GLP-1 medications with cannabis
The evaluation of auditory function was conducted by measurement of auditory brainstem responses (ABR) prior to and at intervals of 5, 16, and 23 days subsequent to the initiation of the treatment