a narrative review
The critical distinction is reversibility and risk profile: Retatrutide is a weekly injection with temporary, manageable side effects versus a permanent surgical intervention with non-trivial operative risk
Testosterone provides powerful anti-catabolic effects that protect muscle during energy deficits
Reproduced from Wilding et al
Because retatrutide is still investigational, important unanswered questions remain about long-term cardiovascular effects, durability of weight loss, ongoing tolerability, and safety across broader patient populations, which is one reason reputable clinics, including Relive Health centers nationwide, are not offering retatrutide at this time
individual outcomes depend on clinical eligibility, biology, and lifestyle