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Acetyl-l-carnitine, known for its neuroprotective properties, plays a key role in brain and nerve health and energy metabolism

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Bennett, J

In this regard, it can be noted that transcription of the gdhA gene initiates from two promoters, one weak, constitutively expressed, called gdhA P1, and another, more potent, called gdhA P2, transactivated by GdhR, a transcriptional regulator whose DNA binding is inhibited by -ketoglutarate (Pagliarulo et al., 2004)

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