However, other studies suggest that cyclosporin A upregulates gingival SHH (Sonic hedgehog protein) expression in vitro, while in vivo that inhibition of the SHH pathway counteracts the stimulatory effect of cyclosporin A on gingival fibroblast proliferation
Small molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levels
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