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Once-weekly subcutaneous retatrutide administration heightened the risk of gastrointestinal and hypersensitivity incidents, typically non-severe

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Population: Adults aged 18 years with type 2 diabetes mellitus (T2DM) and/or obesity (BMI 30 kg/m2)

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[1] When to seek medical advice: Persistent abdominal pain or difficulty swallowing No bowel movement within three days of starting ispaghula Unexplained weight loss or rectal bleeding Signs of allergic reaction (rash, itching, swelling, difficulty breathing) Patients should consult their GP or pharmacist before starting ispaghula, especially if they have pre-existing medical conditions or are taking multiple medications