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In some embodiments, a formulation described herein, further comprises a gelling agent (e.g., poloxamer 407) and provides release of the therapeutic agent over a period of from about 2 days to about 7 days

See instructions for reconstitution/injection/disposal procedures for 1) Pre-filled Dual Chamber Syringe available in 300 mg or 400 mg strength syringes [see Dosage and Administration (2.6)], and 2) Single-dose vials available in 300 mg or 400 mg strength vials [see Dosage and Administration (2.7)]

For example, synthetic estrogens such as ethinylestradiol, commonly derived from contraceptives, have demonstrated the capacity to feminize male fish at concentrations below one nanogram per liter, resulting in reproductive and developmental abnormalities

Thats human skin, measured, published, and peer-reviewed

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