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The drugs also boast other health benefits, such as protection against cardiovascular disease

Andrs E et al

Incretin action in the pancreas: potential promise, possible perils, and pathological pitfalls

Chai, W

How GLP-1 agonists work Multiple mechanisms: Slow gastric emptying (food stays in stomach longer, you feel full longer) Signal satiety to brain (reduce hunger at neurological level) Improve insulin sensitivity (better blood sugar control) Reduce cravings (especially for hyperpalatable foods) May increase metabolism slightly Why they're so effective: They address the biological drivers of overeating, not just willpower

In order to test out Drucker's hypothesis, Wong induced sepsis in some mice, a condition which causes extensive inflammation throughout the body and organ damage