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Study found that increasing endogenous and exogenous intestinal SCFAs can stimulate intestinal endocrine cells to secrete GLP-1 and PYY by binding to GPR41 and GPR43 (Tian et al., 2024)

With continued medication use, spontaneous resolution has been documented at four to six weeks and up to four months

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Metformin is generally safe for most people, but there are a few exceptions

The titration schedule allows your body to adapt to the new medication and reduces side effect risk