Application of 10 "]2 M Nel -AnglV and Dihexa in ballistically transfected hippocampal slices significantly increase spine densities (Figure 7) implying that such changes may in fact be occurring in the intact hippocampus
Lyophilized peptides are usually stable at room temperatures for several weeks or more, so if they will be utilized within weeks or months such storage is typically adequate
This type of study is important for several reasons: it tells us how long the peptide remains active in the body, what breakdown products are formed (which could themselves have biological activity or be used as markers in drug testing), and helps explain why AOD9604 needs to be administered in certain ways to remain effective
These include vegetarians, vegans, older adults, and those with stomach problems
Ko et al., 2007
Proper handling, sterile injection technique, and dosage control are critical for safety