Honestly, I think this actually works and especially after children and after menopausal changes - from experience of patients who have had it, they really rate it
Phase 2 trial (NEJM 2023) used a structured ramp to 12 mg/week but at trial doses of 8 mg and 12 mg, dropout from gastrointestinal events was substantial
In line with the IR-senescence data, low effective doses of FOXO4-DRI were well tolerated in normal IMR90 compared to ABT-737 while being very potent against doxorubicin-senescent cells at higher doses
So does too much B12 make your blood thick and activate the clotting Factor
The primary difference for researchers is its enhanced stability and solubility
Roberts R, Hodson L, Dennis AL, Neville MJ, Humphreys SM, Harnden KE, et al