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TFEB, a master regulator of autophagy and lysosomal biogenesis, can be modulated pharmacologically

A recent systematic review and a meta-analysis of nearly 2.5 million cases [372] demonstrated no significant increase in congenital malformations after statin therapy

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These compounds can be combined with sugars, carboxylic acids, alcohols, amines, or other hydrogen bond-containing compounds to form deep eutectic solvents