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N-acetylcysteine, or NAC, is a supplement that works in two ways: It provides cysteine, which is the rate-limiting amino acid for glutathione production It can also act as a direct antioxidant to scavenge ROS (NO2 and HOX)[ref][ref] The main antioxidant mechanism for NAC is by increasing glutathione levels

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Hardening refers to the process of repairing a barrier to compensate for any existing damages

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Acid tolerance in Rhizobium meliloti strain WSM419 involves a two-component sensor-regulator system