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The model shows that overexpression of genes on chromosome 21 and an increase in oxidative stress can explain the metabolic profile of Down syndrome

Hou Y, Jin J, Duan H, Liu C, Chen L, Huang W et al (2022) Targeted therapeutic effects of oral inulin-modified double-layered nanoparticles containing chemotherapeutics on orthotopic colon cancer

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[19] [21] Typical adult doses for the treatment of vitamin C deficiency range from 200 mg to 1 g daily, administered intravenously, with higher doses (up to 100 grams per day) reserved for specific clinical protocols under close supervision