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[DOI] [PMC free article] [PubMed] [Google Scholar] 197.Lopez-Tobon A., Shyti R., Villa C.E., Cheroni C., Fuentes-Bravo P., Trattaro S., Caporale N., Troglio F., Tenderini E., Mihailovich M., et al

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Should you change it with each dose

10.1016/j.bbrc.2008.05.031 Biochem

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Severe skin reactions, though rare, can be more troublesome and may necessitate discontinuation of the medication