doi: 10.1001/jamanetworkopen.2024.36783
"The lack of standardized production and FDA oversight makes it difficult to assess the consistency and potency of oral formulations," explains Dr
Current treatments are limited and often lead to significant side effects, underscoring the need for new, well-tolerated options
Persistent fatigue beyond week 6 may indicate inadequate nutrition, dosing imbalance, or an unrelated condition requiring provider evaluation
For the study, Wong induced systemic inflammation in mice by either injecting them with a bacterial cell wall component or a bacterial slur to induce sepsis, an extensive inflammation throughout the body that leads to organ damage
The SURMOUNT-4 trial found over 50 percent of tirzepatide weight loss rebounded over 52 weeks