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10.1186/s12943-018-0856-3 115 LiuZ.ShiB.WangY.XuQ.GaoH.MaJ.et al (2022c)

The SURMOUNT-1 trial (tirzepatide, published in NEJM 2022) demonstrated that participants with obesity or overweight without diabetes who received tirzepatide experienced weight reductions of 16.0% (5mg), 21.4% (10mg), and 22.5% (15mg) over 72 weeks