Furthermore, the metabolism of PUFAs is related to the formation of toxic byproducts, especially 4-hydroxynonenal (4-HNE), leading to the initiation of ferroptosis (Zhong and Yin, 2015)
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Currently, it is now known whether the genetic polymorphisms of these oxidative stress enzymes play a role in the development of endometriosis
Beyond angiogenesis, HIF-1 advances invasion via EMT induction and upregulates matrix remodelers such as LOX and MMPs, associating with metastasis and poor prognosis in breast cancer
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