Where to inject: The back or outer portion of the upper arm, in the fatty area between your shoulder and elbow
It stores and concentrates the bile produced by the liver
Am J Physiol Endocrinol Metab 290(6):E1118-1123
Recently, a phase II multicentre, double-blind, randomized controlled trial including 338 adults with obesity were administered retatrutide (1, 2 mg starting dose increased to 4, 2 mg starting dose increased to 8, 2 mg starting dose increased to 12 mg) compared to placebo over 48 weeks [64]
Some providers offer tirzepatide sublingual dosing , which has its own absorption characteristics
Mounjaro vs Retatrutide: Combining the Two (Rationale + Risk) At a glance Mounjaro mechanism / dual agonist: GIP + GLP-1 receptors Retatrutide mechanism / triple agonist: GIP + GLP-1 + glucagon receptors Mounjaro approval status / FDA-approved since May 2022 for type 2 diabetes Retatrutide approval status / investigational