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Tumors have evolved a unique microenvironment, and typically display a more acidic condition, hypoxia, overexpressed reactive oxygen species (ROS), and glutathione (GSH) owing to their rapid proliferation and metabolism (Mura et al., 2013

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The luteinizing hormone receptor and steroidogenesis in Leydig cells. Endocrine Reviews , 19(2), 187223

Lee YB, Kim SJ, Park SM, Lee KH, Han HJ, Yu DS, Woo SY, Yun ST, Hamm S-Y, Kim HJ (2016) Immunomodulatory effects of Deokgu thermomineral water balneotherapy on oxazolone-induced atopic dermatitis murine model

Preclinical work on GHK-Cu supports a role in collagen synthesis and tissue repair, though human trial data is limited

[DOI] [PubMed] [Google Scholar] 11.Nguessan B