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Vitamin B12 injections: These are commonly used in situations of severe shortage or problems with malabsorption

Velkov, S., Ott, J

This area of physiology is particularly relevant in modern medicine, as many chronic diseases, such as cardiovascular, neurological

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Its comparison table lists their typical clinical use as cardiovascular and renal protection, and calls them complementary to incretin therapy rather than a direct substitute

If you develop a persistent, unexplained change in bowel habit particularly if you are aged 40 or over or have other risk factors your GP may wish to assess you in line with NICE guidance on suspected cancer (NG12), which sets out referral thresholds for persistent bowel changes