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Abstract Recently, two oral-administered peptide pharmaceuticals, semaglutide and octreotide, have been developed and are considered as a breakthrough in peptide and protein drug delivery system development

Thus, future studies should include other inflammation-related biomarkers which may explain part of the variance in the clinical neuropsychiatric symptoms, including autoimune responses, the cytokine network, the NLRP3 inflammasome, and hypernitrosylation

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